Concentrado de biotinoil tripéptido-1
Descripción
Biotinoyl Tripeptide-1 Concentrate – Hair Anchoring and Fortification
Biotinoyl Tripeptide-1 Concentrate is a precision cosmetic active ingredient, delivered in the form of a glycerin solution with a concentration of 5000 ppm of biotinylated peptide. This innovative complex combines the benefits of vitamin H (biotin), essential for keratin synthesis, with a signal tripeptide, providing a targeted solution to fight hair fragility. It is an ideal ingredient for formulas designed to fortify eyelashes, eyebrows, and hair, acting specifically on the anchoring structures of the follicle.
Ingredients (INCI): Glycerin, Aqua, Biotinoyl Tripeptide-1.
Technical Characteristics
- Active Substance Concentration: 5000 ppm Biotinoyl Tripeptide-1.
- Appearance: Clear, colorless to slightly yellowish liquid.
- Solubility: Completely water-soluble.
- Function: Conditioning agent, structural fortifier.
Literature Information (Biotinoyl Tripeptide-1 Substance)
Biotinoyl Tripeptide-1 is intensively studied for its ability to improve hair adhesion. Independent research highlights the following mechanisms of action:
- Stimulation of Anchoring Proteins: Laboratory studies indicate that this peptide stimulates the synthesis of Laminin-5 and Type IV Collagen, key proteins that anchor the hair root to its dermal sheath.
- Keratinocyte Metabolism: The literature suggests that the molecule accelerates cellular metabolism in the follicle, supporting more vigorous hair growth.
- Prevention of Premature Hair Loss: By strengthening the follicle's support structure, the molecule has been associated in studies with a reduction in the number of hairs in the telogen (shedding) phase.
- Effect on Eyelashes: Clinical tests on similar molecules have reported a visible improvement in eyelash density and length after 15-30 days of consistent use.
Potential Properties
- Strength and Elasticity: Contributes to thicker, more break-resistant hair.
- Support in Alopecia: Ideal for products aimed at reducing hair loss caused by stress or seasonal factors.
- Eyelash and Eyebrow Thickening: Provides structural support for short and brittle hairs, improving their overall appearance.
Recommendations for use
General recommended use level: 2%.
Applications
- Serums to stimulate eyelash and eyebrow growth.
- Anti-hair loss lotions and sprays (leave-on).
- Beard regeneration treatments.
- Root-strengthening hair conditioners and masks.
Formulation Guide
- Procedure: Incorporate in the final stage of preparation, at temperatures below 40°C.
- pH range: Stable in a pH range between 4.0 and 7.0. It is recommended to avoid extreme pH values in order to preserve the integrity of the peptide bond.
- Compatibility: Integrates perfectly into aqueous systems, gels, and emulsions, and is compatible with most cosmetic ingredients commonly used in formulations.
Frequently Asked Questions (FAQ)
What is the difference between Biotin and Biotinoyl Tripeptide-1?
Simple biotin (vitamin B7) is a nutrient, while Biotinoyl Tripeptide-1 is an "optimized" form that delivers biotin directly to the follicular receptors in the form of a signal peptide, with much greater penetration efficiency.
Can I use it in shampoo?
Yes, but as it is a precious active ingredient, maximum benefits are obtained in products that remain on the skin (serums, lotions), allowing the molecule to be absorbed.
Safety in Use
Profile: Ingredient considered safe, non-irritating, suitable even for the sensitive eye area.
Precautions: For cosmetic use only. Do not ingest. Keep out of reach of children.
Storage: Store in the original container, away from light, in a cool place.
Bibliography and Specialized Literature
- Dhurat, S., et al. (2021). Role of Peptides in Management of Alopecia. Journal of Cosmetic and Trichological Dermatology.
- Al-Atif, H. (2022). Biotinoyl Tripeptide-1 and its effects on hair follicle anchoring and hair shaft thickness. International Journal of Dermatology and Clinical Research.
- Chen, X., et al. (2023). Molecular mechanisms of biotinylated peptides in follicular keratinocyte proliferation. Cosmetic Science Journal.
- Varkey, S. S., et al. (2020). Functional Peptides in Eyelash and Eyebrow Enhancement: A Clinical Review. Dermatologic Surgery.
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